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美国进口鱼藤酮CAS 83-79-4Sigma-R8875

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品牌: 美国sigma
单价: 290.00元/1G
起订: 1 1G
供货总量: 1000 1G
发货期限: 自买家付款之日起 1 天内发货
所在地: 浙江 杭州
有效期至: 长期有效
最后更新: 2018-08-28 10:18
浏览次数: 19
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中文名(CN) 英文名(EN) CAS No. 规格(SP) 报价(CNY) 产地(From) 类别(Key)
鱼藤酮 Rotenone,≥95% 83-79-4 1G 290.00 Sigma-R8875 生化试剂
鱼藤酮 Rotenone,≥95% 83-79-4 5G 980.00 Sigma-R8875 生化试剂
鱼藤酮 Rotenone,≥95% 83-79-4 10G 1500.00 Sigma-R8875 生化试剂
鱼藤酮 Rotenone,≥95% 83-79-4 25G 2360.00 Sigma-R8875 生化试剂
鱼藤酮 Rotenone,≥95% 83-79-4 100G 9800.00 Sigma-R8875 生化试剂

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产品名称 鱼藤酮 : Rotenone ——【产品编号:SIGMA-R8875】
CAS编号 83-79-4
别名 鱼滕酮,鱼滕精,鱼藤精,毒鱼藤素,毒鱼滕素,nicouline,tubatoxin,Nekoe,rotenoid
级别 科学级
纯度&分析 ≥95%,HPLC
Tips 此产品纯度较高,可用于生化分析、农药研究、培养或其他科研领域。
分子式 C23H22O6
分子量 394.42
储存条件 常温避光保存。
性质
assay ≥95%
bp 210-220 °C/0.5 mmHg(lit.)
mp 159-164 °C(lit.)
原产地 美国
描述

Biochem/physiol Actions

Inhibitor of mitochondrial electron transport at NADH:ubiquinone oxidoreductase. It is readily absorbed through the exoskeletons of arthropods, but poorly absorbed cutaneously or from the gastrointestinal tract of mammals. Rotenone is used to induce a Parkinson-like syndrome as an experimental model in rats.

Inhibitor of mitochondrial electron transport. Neurotoxic agent that can produce a Parkinson-like condition as an animal model for study of etiology and interventions.

供货状态 True
参考文献

Fukami, J.I., et al. Science 155, 713, (1967)

Kuznetsov, A.V., et al., Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells. Nat. Protoc. 3, 965-76, (2008)

Verma, R., and Nehru, B., Effect of centrophenoxine against rotenone-induced oxidative stress in an animal model of Parkinson's disease. Neurochem. Int. 55, 369-75, (2009)

Qian, W., and Van Houten, B., Alterations in bioenergetics due to changes in mitochondrial DNA copy number. Methods , (2010)

Shaham, O., et al., A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media from cultured muscle cells Proc. Natl. Acad. Sci. U. S. A. 107, 1571-5, (2010)

Rey, B., et al., Up-regulation of avian uncoupling protein in cold-acclimated and hyperthyroid ducklings prevents reactive oxygen species production by skeletal muscle mitochondria. BMC Physiol. 10, 5, (2010)

Serviddio, G., and Sastre, J., Measurement Of Mitochondrial Membrane Potential And Proton Leak. Methods Mol. Biol. 594, 107-21, (2010)

Qian, W., and Van Houten, B., Alterations In Bioenergetics Due To Changes In Mitochondrial DNA Copy Number. Methods 51, 452-7, (2010)

Caboni, P., et al., Rotenone, deguelin, their metabolites, and the rat model of Parkinson's disease Chem. Res. Toxicol. 17, 1540-1548, (2004)

Uversky, V.N., Neurotoxicant-induced animal models of Parkinson's disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration Cell Tissue Res. 318, 225-241, (2004)

Merck 14,8271

Beil. 19,II,438

Aldrich MSDS 1, 1592:A / Corp MSDS 1 (2), 3055:C / FT-IR 1 (2), 99:A / FT-NMR 1 (2), 923:A / IR-Spectra (3), 907:G / IR-Spectra (2), 794:D / NMR-Reference 2 (2), 99:C / RegBook 1 (2), 1701:B / Sax 6, 2373 / Sigma FT-IR 1 (2), 884:B / Structure Index 1, 270:D:6

类型 BSZH 有机化学试剂
安全信息
符号 GHS06GHS09
信号词 Danger
危险声明 H301-H315-H319-H335-H410
警示性声明 P261-P273-P301 + P310-P305 + P351 + P338-P501
危害码 T,N
风险声明 25-36/37/38-50/53
安全声明 22-24/25-36-45-60-61
RIDADR UN 2811 6.1/PG 3
WGK德国 3
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